Coverjunkie asked George Lois about the favorite covers he designed himself:

- #3 Esquire, John Kennedy/Dr. Martin Luther King/Robert Kennedy, 1968:
“I plead guilty to shockingly irreverent concepts for many covers. But the ’60s, at times, pleaded for equally shocking reverence. Our assassinated leaders, the three most mourned Americans since FDR, hauntingly watch over Arlington National Cemetery. For Esquire ’s definitive 35th anniversary issue, in a hagiographic fantasy, I paid homage to an idealized, saint-like John Kennedy, Robert Kennedy and Dr. Martin Luther King in this dreamlike epitaph on the murder of American goodness.”

For (the few) people out there don't know him, he designed classics for esquire in the 60's that are also shown in the MoMA New York;
He stripped the cover down to a graphically concise yet conceptually potent image. He was probably the most provocative in the history of the magazine industry...
see more here

All interviews appear in The Coverjunkie Magazine,
I talked with him along with aces like Arem Duplessis, Richard Turley, Rodrigo Sanchez, Matt Willey, Robert Newman & Francesco Franchi